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Dry skin with blemishes (acne scars, sun spots)

Also called t-AMCHA, Tranexamic Acid (trans-4 aminomethylcyclohexanecarboxylic acid - TA), is widely used as a soothing and whitening agent.

HA (Hyaluronic Acid) has important hydrating and anti-aging properties. The molecular weight of HA influences its penetration into the skin and its biological activity.

What do the studies show?

As demonstrated in a double-blind clinical study during the dry and cold winter season, topical tranexamic acid improves the function of the stratum corneum by increasing skin hydration. Furthermore, it can promote skin barrier repair: a randomized, vehicle-controlled study conducted on 30 patients demonstrated that local treatment with tranexamic acid significantly reduced TEWL (transepidermal water loss—the continuous evaporation of water through the outer layers of the epidermis) and skin surface pH in subjects with rosacea, and improved stratum corneum hydration. Tranexamic acid has been shown to inhibit melanogenesis, which is responsible for the formation of skin spots; in summary, improved skin barrier function, reduced TEWL, and inhibited melanin synthesis make tranexamic acid an effective active ingredient for the treatment of dry skin with hyperpigmentation. Furthermore, the specific combination of the two active ingredients (Hyaluronic Acid and Tranexamic Acid ) has demonstrated their synergistic effect on skin conditions related to hyperpigmentation: the topical application of this combo inhibits the activity of tyrosinase and the production of melanin under UVB rays.